Activation Energy:

The minimum amount of energy required for effective collusion during a chemical reaction is called activation energy.

Significance of Activation Energy:

All chemical reactions require activation energy to break chemical bonds and begin the reaction. The need for activation energy acts as a barrier to the beginning of the reaction.

Reference of Activation Energy in Enzymes:

Enzymes lower such barriers by decreasing the requirement of activation energy of enzymes, reactions proceed at a faster rate Enzymes lower the activation energy in several ways. They do so by:

1. Altering the shape of the substrates and reducing the amount of energy required to complete the transition.
2. Disrupting the charge distribution.
3. Bringing substrate in the correct orientation to react.